For patients 12 years and older with chronic graft-versus-host disease (chronic GVHD) after 2 prior systemic treatments did not work.
For patients 12 years and older with chronic graft-versus-host disease (chronic GVHD) after 2 prior systemic treatments did not work.
For US Residents Only
For US Residents Only
During a blood stem cell transplant, stem cells from a donor (the graft) are added to your body (the host).
When this happens, it can lead to chronic GVHD. Chronic GVHD causes your immune system to become unbalanced, creating too many of some cells and molecules, and not enough of others. This leads to inflammation (swelling) and fibrosis (hardening, scarring), which can damage your organs.
Health care providers may try different medicines, including immunosuppressants, to help treat chronic GVHD. However, for some people that might not be enough, and they will need a different approach.
REZUROCK can help REBALANCE your immune system. It is the only approved medicine for chronic GVHD that blocks the ROCK2 pathway in your body. This may reduce the INFLAMMATION and FIBROSIS that can happen with chronic GVHD.
See the results for REZUROCK
What are inflammation and fibrosis?
Many systems in the body work through what are called "PATHWAYS." These pathways are a series of actions that take place among cells and molecules within the body. One such pathway is called "ROCK2."
In people with chronic GVHD, this ROCK2 pathway is too active. This leads to a decrease in cells and molecules that help keep the immune system in check and an increase in cells and molecules that cause inflammation and fibrosis. The result is an immune system that is OUT OF BALANCE.
GVHD, graft-versus-host disease.
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MAT-US-2201641-v1.0-05/2022 Last updated: May 2022
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