During a blood stem cell transplant, stem cells from a donor (the graft) are added to your body (the host).
When this happens, it can lead to chronic GVHD. Chronic GVHD causes your immune system to become unbalanced, creating too many of some cells and not enough of others. This leads to inflammation (swelling) and fibrosis (scarring), which can damage your organs.
Tablet not actual size.Find out the difference REZUROCK can make.
Most medicines for chronic GVHD are immunosuppressants (ih-myoo-no-suh-preh-sents). These medicines suppress (reduce the strength of) your immune system. While these medicines can help treat your condition, they can also lower your body’s ability to fight something it recognizes as being an invader, such as an infection.
REZUROCK is different. It can help REBALANCE your immune system. REZUROCK is the only approved medicine that blocks the ROCK2 pathway in your body and may reduce the symptoms of inflammation and fibrosis.Find out the difference REZUROCK can make.
GVHD, graft-versus-host disease.
REZUROCKTM (belumosudil) is a prescription medicine used to treat adults and children 12 years of age and older with chronic graft-versus-host disease (chronic GVHD) after you have received at least 2 prior treatments (systemic therapy) and they did not work. It is not known if REZUROCK is safe and effective in children less than 12 years old.
Before taking REZUROCK, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. REZUROCK may affect the way other medicines work, and other medicines may affect the way REZUROCK works.
Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.
How should I take REZUROCK?
What are the possible side effects of REZUROCK?
The most common side effects of REZUROCK include:
Your healthcare provider may change your dose of REZUROCK, temporarily stop, or permanently stop treatment with REZUROCK if you have certain side effects.
REZUROCK may affect fertility in males and females. Talk to your healthcare provider if this is a concern for you.
These are not all the possible side effects of REZUROCK. Call your doctor for medical advice about side effects.
Please see full Prescribing Information.
You are encouraged to report side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088. You may also contact Kadmon Pharmaceuticals, LLC, at 1-877-377-7862 to report side effects.
REZUROCKTM (belumosudil) is a prescription medicine used to treat adults and children 12 years of age and older with chronic graft-versus-host disease (chronic GVHD)
REZUROCKTM (belumosudil) is a prescription medicine used to treat adults and children