REZUROCK was evaluated in 2 clinical studies that included a total of 186 people.
people in the ROCKstar study found symptom relief
Many people found symptom relief within 4 to 8 weeks.
Everyone responds to medicine differently. Some people may take longer to respond, especially if their organs are damaged by scarring.
In some people, REZUROCK also reduced the need
for steroids and other immunosuppressants.
People who found symptom relief with REZUROCK were at different stages of their treatment journey and
Immunosuppressants (ih-myoo-no-suh-preh-sents), such as steroids, suppress (reduce the strength of) your immune system.
What are the side effects of REZUROCK?
In clinical studies, side effects with REZUROCK were similar to those expected in people receiving steroids and other medicines for chronic GVHD.
There were NO NEW CASES of cytomegalovirus (CMV) infection and only 1 case of recurring CMV infection.
CMV is a common serious infection that can happen in people who have had a blood stem cell transplant.
There was a low rate of serious cytopenia (site-oh-pee-nia), a condition that causes a lower-than-normal number of certain blood cells.
Be sure to tell your health care provider about any side effects you have. They may be able to help you find ways to manage them.
GI, gastrointestinal; GVHD, graft-versus-host disease.
REZUROCKTM (belumosudil) is a prescription medicine used to treat adults and children 12 years of age and older with chronic graft-versus-host disease (chronic GVHD) after you have received at least 2 prior treatments (systemic therapy) and they did not work. It is not known if REZUROCK is safe and effective in children less than 12 years old.
Before taking REZUROCK, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. REZUROCK may affect the way other medicines work, and other medicines may affect the way REZUROCK works.
Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.
How should I take REZUROCK?
What are the possible side effects of REZUROCK?
The most common side effects of REZUROCK include:
Your healthcare provider may change your dose of REZUROCK, temporarily stop, or permanently stop treatment with REZUROCK if you have certain side effects.
REZUROCK may affect fertility in males and females. Talk to your healthcare provider if this is a concern for you.
These are not all the possible side effects of REZUROCK. Call your doctor for medical advice about side effects.
Please see full Prescribing Information.
You are encouraged to report side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088. You may also contact Kadmon Pharmaceuticals, LLC, at 1-877-377-7862 to report side effects.
REZUROCKTM (belumosudil) is a prescription medicine used to treat adults and children 12 years of age and older with chronic graft-versus-host disease (chronic GVHD)
REZUROCKTM (belumosudil) is a prescription medicine used to treat adults and children