For patients 12 years and older with chronic graft-versus-host disease (chronic GVHD) after 2 prior systemic treatments did not work.
For patients 12 years and older with chronic graft-versus-host disease (chronic GVHD) after 2 prior systemic treatments did not work.
For US Residents Only
For US Residents Only
Chronic GVHD causes your immune system to become unbalanced. In people with chronic GVHD, the immune system overreacts, creating too many of some cells and molecules, and not enough of others. This leads to inflammation (swelling) and fibrosis (hardening, scarring).
is swelling that occurs because your body is trying to protect itself.
Inflammation that goes on for a long time, like in chronic GVHD, may cause damage to your body.
is the growth of scar tissue that hardens and keeps your organs from working properly.
In some people, fibrosis happens when inflammation goes on for a long time. It is also possible for scar tissue to form without any inflammation.
Common symptoms of chronic GVHD include
|
|
||||
|
|
||||
|
|
||||
|
|
Skin rashes, changes in skin color and skin thickening or tightening
Stiff joints and trouble
using your fingers,
hands, elbows, knees
or ankles
Dry eyes or vision changes
Sensitivity to food, irritation and dryness of the mouth and difficulty swallowing food
Chronic cough, shortness of breath or difficulty breathing
Nausea, vomiting, diarrhea or loss of appetite
General decline in
health, including fatigue
Abnormal liver function, measured by various tests
Some people also have
|
|
Lack of energy
Reduced ability to do daily tasks
If you have chronic GVHD and are still experiencing symptoms, talk with your health care team about your treatment options.
GVHD, graft-versus-host disease.
© 2022 Kadmon Pharmaceuticals, LLC.
All Rights Reserved.
This site is intended for use by US Residents only.
MAT-US-2201643-v1.0-05/2022 Last updated: May 2022
For Health Care Professionals
Stay Informed
